Review (2026)
By Alexandru Vieru · Founder & Editor · Not medical advice
Independently researched · scored on our public 4-criteria methodology
One of the few clinics here that names its actual pharmacies and medical groups, publishes every plan length with its billing cadence, and bundles metabolic lab work every six months. But it's priced at the top of this set and it doesn't ship to 11 states.
See our top-rated pick: Wellorithm →Summarize this page with
Short answer
Enhance.MD scores 7.5/10 (#14 of 53 clinics). $212/mo, billed every 48 weeks is the ongoing rate, not the number you'll see advertised. Enhance.MD fronts an introductory $112 first month, and $212/mo, billed every 48 weeks is what it costs from month two onward. Budget for the ongoing figure, not the headline. There is also a flagged concern. See Is Enhance.MD legit? below.
Our verdict
Enhance.MD earns 7.5/10 and ranks #14 of 53online GLP-1 clinics we've scored. One of the few clinics here that names its actual pharmacies and medical groups, publishes every plan length with its billing cadence, and bundles metabolic lab work every six months. But it's priced at the top of this set and it doesn't ship to 11 states.
Not currently a paying partner. Enhance.MD is an affiliate partner of ours, but we have paused it since 2026-10-08: its affiliate link loses our tracking ID on Enhance.MD's own site (enhance.md redirects the page the link lands on and drops the parameters), so a sign-up through it would not be credited to us. We removed the link until the affiliate network supplies one that keeps the ID. There is no affiliate link on this page and we earn nothing from it today. The score, the price and the evidence are unchanged.
Pricing details
$212/mo, billed every 48 weeks is the ongoing rate, not the number you'll see advertised. Enhance.MD fronts an introductory $112 first month, and $212/mo, billed every 48 weeks is what it costs from month two onward. Budget for the ongoing figure, not the headline.
Verified live 2026-09-01 on enhance.md/product/core-semaglutide (the price grid) and enhance.md/weight-loss. The product is GLP-1 Core, compounded semaglutide: $212/mo on the 12-month plan (billed every 48 weeks), $224/mo on 6-month, $237/mo on 3-month, $249/mo month-to-month. Same price at every dose, with medication, ongoing provider care, metabolic lab testing every 6 months and free shipping included. GLP-1 Advanced (compounded tirzepatide) runs $280/$296/$313/$329 across the same four plan lengths. The headline numbers on the site are first-month promos, not the ongoing rate: the sitewide banner reads "Labor Day Sale... Save up to $150 on your first order" and the weight-loss page prints "Starting at $112 first month, $212/month"; stacking codes SUMMER100/SUMMER50 are also shown. Enhance.MD's own affiliate creative advertises a lower intro still. "$49 on semaglutide, $99 on tirzepatide, first month of a 12-month subscription only, new subscribers only, cannot be combined." All of those are first-month-only, so none is recorded as the price; $212 is the rate that actually recurs. A separate Microdosing Tirzepatide tier at $169/mo is NOT used here. Enhance.MD's own page frames it as longevity-focused metabolic support where "weight loss may occur, but isn't the primary aim," the same reason Gala Health's $149 microdosing tier is excluded from a weight-loss ranking.
Plans and prices
| Plan | Price | Term | What it covers |
|---|---|---|---|
| 6-month | $224/mo | billed every 24 weeks, ”Save 10% + $100 off first order” | Includes medication, clinician visits, shipping, per Enhance.MD |
| 3-month | $237/mo | billed every 12 weeks, ”Save 5% + $100 off first order” | Includes medication, clinician visits, shipping, per Enhance.MD |
| 1-month | $249/mo | billed every 4 weeks, ”$50 off first order” | Includes medication, clinician visits, shipping, per Enhance.MD |
Enhance.MD's own figures, read up to 2026-09-30 on enhance.md.
Classified as “First-month rate that rises”. See how we classify every clinic's price →
Sources: Pricing verified on enhance.md
Your first charges with Enhance.MD
What leaves your card and when, on the cheapest plan we price, if a clinician approves you. Figures marked “our arithmetic” are worked out from Enhance.MD's own prices.
- At checkout$2,544The whole 48 weeks(our arithmetic)
- After 48 weeksNot publishedRenewal for the next term. The renewal price isn't published; check before it renews
The term total is $212 × 12 four-week cycles, our arithmetic from Enhance.MD's per-month figure.
From Enhance.MD's prices, read 2026-10-05 on enhance.md.
What Enhance.MD's ads say, and what the fine print says
Each row sets a claim from Enhance.MD's sales pages beside its terms or another of its own pages, as we read them. Only the places where the two differ are shown.
| Topic | On the sales page | In the terms or elsewhere on its site |
|---|---|---|
| The price | $112 for the first monthenhance.md, read 2026-10-05 | $212/mo from the second month onenhance.md, read 2026-10-05 |
| How you pay | $212/moenhance.md, read 2026-10-05 | Charged $2,544 at checkout for the whole 48 weeks (our arithmetic from its prices)enhance.md, read 2026-10-05 |
Enhance.MD’s starting price in our records
We recorded $212 on Sep 1, 2026, and the starting price in our records hasn’t changed since.
A change can be the clinic moving its price or us correcting an earlier reading. The full series for every clinic is in price-history.csv.
What changed since we last checked
No change to Enhance.MD’s plan rows or list of states in our record since we started recording them. Changes to its starting price are in the section above.
A change can be Enhance.MD moving a price, or us reading a page we hadn’t read before or correcting an earlier reading. Dates are when the change entered our record.
Before you sign up with Enhance.MD
Each line is from Enhance.MD's own pages or a public record, with the date we read it. Where we hold no reading, the line is left out rather than guessed.
- What the price covers
- Medication: included. Enhance.MD's page: “Your subscription includes four weeks of semaglutide medication, ongoing provider care and support, metabolic lab testing every six months, essential supplies, wellness coaching, and full platform access with educational content.” Clinician visits: included. Enhance.MD's page: “Your subscription includes four weeks of semaglutide medication, ongoing provider care and support, metabolic lab testing every six months, essential supplies, wellness coaching, and full platform access with educational content.” No extra fees, per Enhance.MD: “No hidden fees or surprise charges. Just clear, honest pricing from day one.” (enhance.md, read 2026-10-07)
- 12-month total
- About $2,544 for the first 12 months, by our arithmetic from Enhance.MD's published prices. $212/mo is the 12-month tier, billed every 48 weeks. The shorter plans are real, published, and cost more: $224/mo (6-month), $237/mo (3-month), $249/mo month-to-month. $2,988 over a year if you don't commit. The first month is currently discounted by a promotion ($112 under the Labor Day banner, less still under the affiliate creative's $49 intro), which is excluded here because it applies once and the terms of the offer change; the ongoing rate is what's modelled. Enhance.MD bills the 12-month plan every 48 weeks; it doesn't print the charge, so $2,544 (12 x $212) is our calculation. 48 weeks ends before month 12, so if the plan renews, a second charge falls inside the year; the site doesn't say whether it renews automatically. (our records, read 2026-10-05)
- Cancelling and refunds
- Not published where we looked. The only refund language is scoped to onboarding: “if at any point during the onboarding process you are found ineligible for our formulation, Enhance.MD will provide a full refund of 100% of your initial payment.” Nothing covers cancelling once treatment has started. (our records, read 2026-09-14)
- States served
- 40 of 51. Not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee, West Virginia.
- Lab work
- Before you start: Enhance.MD's pages don't say. Ongoing: included. “Your subscription includes four weeks of semaglutide medication, ongoing provider care and support, metabolic lab testing every six months, essential supplies, wellness coaching, and full platform access with educational content.” (enhance.md, read 2026-10-07)
- Shipping
- Shipping: included. Enhance.MD's page: “Delivery of Medication Every 4 Weeks Ongoing Provider Care & Support Metabolic Lab Testing Every 6 Months Same Pricing - All Doses Free Shipping” (enhance.md, read 2026-10-07)
Check your state and budget
From Enhance.MD’s own pages as recorded in its review. A monthly figure for a plan billed every few weeks or months is our arithmetic.
Compare two Enhance.MD plans
| A: 6-month | B: 3-month | |
|---|---|---|
| Price as published | $224/mo | $237/mo |
| Works out to a month | $224 | $237 |
| First 12 months | $2,688 ($224 × 12) | $2,844 ($237 × 12) |
| Commitment | billed every 24 weeks, ”Save 10% + $100 off first order” | billed every 12 weeks, ”Save 5% + $100 off first order” |
| What it covers | Not stated on the row | Not stated on the row |
| Read on | Sep 30, 2026 | Sep 30, 2026 |
Over the first 12 months, B costs $156 more than A, by the arithmetic shown.
Twelve-month figures assume the price holds and you stay the full year; they leave out anything billed separately.
Questions to ask Enhance.MD at intake
Each one is here because Enhance.MD’s pages left it open when we read them.
- Do I need lab work before starting, and what does it cost? Its pages don't say whether labs are needed or what they cost.
- How do I reach a clinician between visits, and how fast do they reply? We didn't find a published support or messaging commitment.
Is Enhance.MD legit?
What we checked before publishing this page.
- ✓ A U.S.-licensed clinician reviews your case before anything is prescribed
- ✓ Intake includes a real medical questionnaire, not a rubber stamp
- ✓ Named price on their own site ($212/mo, billed every 48 weeks), verified 2026-10-05
- ✓ Ranked by the rubric on our editorial policy page. Payout status never enters into it
Independently verified on Trustpilot: 4.1/5 from 159 reviews (checked 2026-09-01). 32 of those (20%) are from the last 12 months. A rating resting mostly on old reviews reads differently than one built on recent ones. Domain check passed: the profile's own listed website is enhance.md, identical to the domain our affiliate link leads to (enhance.md). Read directly off the profile page, not a search snippet. 159 reviews clears this site's 10-review floor, but only 32 of them are from the last 12 months. The rating leans on an older body of reviews. See reviews →
Watch out for
Enhance.MD doesn't ship to 11 states. Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee and West Virginia. Of the clinics whose state exclusions we record, only Willow (14 states) and MangoRx (12) exclude more, and it's worth checking before you start an intake. One caveat on that list: Enhance.MD's own FAQ says it is "licensed in all 50 states" but has only launched in 40 plus DC, and its published launch list DOES include West Virginia. While its affiliate terms exclude it. We've used the more restrictive list. If you're in West Virginia, confirm directly with Enhance.MD before paying. Separately, the advertised $212/mo requires prepaying a 12-month plan billed every 48 weeks; month-to-month is $249/mo. The Terms of Service say only that subscriptions "auto-renew unless canceled before the next billing cycle" and that "full subscription and payment terms are provided at checkout". What happens if you cancel a 48-week prepay early is not published before purchase, and prescription products "cannot be returned for any reason." (Sources: enhance.md weight-loss, product, FAQ, Terms of Service and Shipping & Returns pages, all verified 2026-09-01; state exclusions from the clinic's affiliate program terms.)
What the research says
Dr. Daniel J. Drucker (Lunenfeld-Tanenbaum Research Institute, University of Toronto. Co-discoverer of GLP-1 biology) reviewed the expanding evidence base for GLP-1 medicines beyond weight loss, including cardiovascular and kidney-disease benefit, alongside open questions on long-term safety that still require more data.
“GLP-1-based therapies for diabetes, obesity and beyond,” Nature Reviews Drug Discovery / Nature Medicine, 2025. More on GLP-1 safety →
Sources: Trustpilot, enhance.md weight-loss, product, FAQ, Terms of Service and Shipping & Returns pages, all verified 2026-09-01; state exclusions from the clinic's affiliate program terms.
Third-party records
What we found outside Enhance.MD's own site. BBB, its named pharmacy partner (or lack of one), and whether it publishes a real HIPAA notice.
Better Business Bureau
No BBB profile found for Enhance.MD (checked 2026-09-01).
No BBB profile found for Enhance.MD LLC (the Delaware entity named in its own Terms of Service). Searched the bbb.org directory directly for "Enhance.MD" across the US: 487 results, none matching this telehealth entity. The closest names returned are unrelated businesses (Enhanced Roofing, Enhanced Payment Systems, Enhance Appliance Services). Absence here is a checked, reported fact. No profile exists, which is different from an unrated or a poorly rated one.
Pharmacy partner
- Rite-Away Pharmacy (San Antonio, TX)
No FDA warning letters. Exact-phrase full-text search on fda.gov for "Rite-Away Pharmacy" and for "Rite Away" returned zero rows for both, checked 2026-09-01.
- Vios Compounding Pharmacy (Livonia, MI)
No FDA warning letters. Exact-phrase full-text search on fda.gov for "Vios Compounding" and for "Vios" returned zero rows for both, checked 2026-09-01.
- Beauty Empower Rx, LLC dba TruMedsRx (Fairfax, VA)
No FDA warning letters. Exact-phrase full-text search on fda.gov for "Beauty Empower Rx" and for "TruMedsRx" returned zero rows for both, checked 2026-09-01.
Unusual for this category: Enhance.MD names all three fulfilment pharmacies outright in its Terms of Service, each with a website, phone, email and street address. Every provider audited in this file before now names none. Each partner was checked individually against the FDA warning-letter full-text search on fda.gov (2026-09-01). Zero letters for all three.
HIPAA disclosure
Published. A real HIPAA-specific notice, checked 2026-09-01. Dedicated "Use and Disclosure of Your Health Information" section running to several hundred words: treatment/operations uses, the specific legal grounds for disclosure without consent (public-health reporting, law enforcement under court order, abuse reporting, health-oversight activity, coroner requests), and the patient's own rights. Access in writing with a written explanation if denied, amendment of incorrect information, and how to complain. Not just a footer HIPAA badge.
Who operates it
Operated by Enhance.MD LLC, 16192 Coastal Highway, Lewes, Delaware 19958. Published on Enhance.MD's own site, checked 2026-09-14. Describes itself as “a patient management platform”, which is the administrative-services framing several clinics in this set use.
Cancelling and refunds
No written cancellation or refund terms found on the site (checked 2026-09-14). The only refund language is scoped to onboarding: “if at any point during the onboarding process you are found ineligible for our formulation, Enhance.MD will provide a full refund of 100% of your initial payment.” Nothing covers cancelling once treatment has started.
19 of the 32 clinics we could read publish no written cancellation terms. We read all 32 and quoted what they say →
Is Enhance.MD legit? Our full legitimacy check →
Sources: Privacy policy
Choose Enhance.MD if
- + You want this kind of clinic
- + You're looking for compounded semaglutide
- + You're looking for compounded tirzepatide
Skip Enhance.MD if
- − Not available in 11 states, including Alabama, Arkansas, Georgia
- − The advertised price is an introductory rate that rises after the first period
- − No cancellation or refund terms where the price is shown
Enhance.MD pros & cons
What we like
- + Publishes the full price grid (all four plan lengths, each with its billing cadence) plus the same price at every dose
- + Names all three partner pharmacies and both medical groups on its own site, which almost nobody in this category does
- + Metabolic lab testing every 6 months and ongoing provider care included in the monthly price, no separate membership fee
What could be better
- − Not available in 11 states, including Alabama, Arkansas, Georgia
- − The advertised price is an introductory rate that rises after the first period
- − No cancellation or refund terms where the price is shown
Quick facts
| Our score | 7.5/10 |
| Starting price | $212/mo, billed every 48 weeks |
| Treatment types | compounded semaglutide, compounded tirzepatide, compounded semaglutide + tirzepatide, microdosing |
| Availability | 40 of 51 states |
| Insurance | Doesn't bill insurance, per its own pages; doesn't take HSA/FSA cards |
| Overall rank | #14 of 53 |
| Price status | Verified 2026-10-05 |
Score breakdown
Sources: Full scoring methodology
How we know. The evidence behind this score
Every criterion below shows what we checked, when, and where you can check it yourself. Where we have no public source on file, the row says so rather than implying one exists. 1 of 4 criteria here is backed by a source you can open.
| Criterion | Score | Last checked | Source you can open |
|---|---|---|---|
| Price & Value (25%) | 6.0 | 2026-10-05 | enhance.md |
| Clinical Oversight (30%) | 8.0 | — | no public source on file |
| Medication Options (20%) | 8.0 | — | no public source on file |
| Transparency & Trust (25%) | 8.0 | — | no public source on file |
How Enhance.MD works
- 1. Online intake. Complete a medical questionnaire and eligibility check (often BMI-based) covering your health history.
- 2. Clinician review. A licensed clinician reviews your information and, if appropriate, prescribes semaglutide or tirzepatide with a dose-titration plan.
- 3. Delivery & monitoring. Your medication ships discreetly to your door, with check-ins and dose adjustments along the way.
Frequently asked questions
How much does Enhance.MD cost?
Enhance.MD starts at $212/mo, billed every 48 weeks (verified 2026-10-05). Final cost depends on your medication and dose.
What does Enhance.MD cost over 12 months?
About $2,544 for the first 12 months, by our arithmetic from Enhance.MD's published prices. $212/mo is the 12-month tier, billed every 48 weeks. The shorter plans are real, published, and cost more: $224/mo (6-month), $237/mo (3-month), $249/mo month-to-month. $2,988 over a year if you don't commit. The first month is currently discounted by a promotion ($112 under the Labor Day banner, less still under the affiliate creative's $49 intro), which is excluded here because it applies once and the terms of the offer change; the ongoing rate is what's modelled. Enhance.MD bills the 12-month plan every 48 weeks; it doesn't print the charge, so $2,544 (12 x $212) is our calculation. 48 weeks ends before month 12, so if the plan renews, a second charge falls inside the year; the site doesn't say whether it renews automatically. (Read 2026-10-05.)
What does Enhance.MD's price include?
Medication: included. Enhance.MD's page: “Your subscription includes four weeks of semaglutide medication, ongoing provider care and support, metabolic lab testing every six months, essential supplies, wellness coaching, and full platform access with educational content.” Clinician visits: included. Enhance.MD's page: “Your subscription includes four weeks of semaglutide medication, ongoing provider care and support, metabolic lab testing every six months, essential supplies, wellness coaching, and full platform access with educational content.” No extra fees, per Enhance.MD: “No hidden fees or surprise charges. Just clear, honest pricing from day one.” (Read 2026-10-07.)
Can I cancel Enhance.MD and get a refund?
Not published where we looked. The only refund language is scoped to onboarding: “if at any point during the onboarding process you are found ineligible for our formulation, Enhance.MD will provide a full refund of 100% of your initial payment.” Nothing covers cancelling once treatment has started. (Read 2026-09-14.)
Does Enhance.MD require lab work?
Before you start: Enhance.MD's pages don't say. Ongoing: included. “Your subscription includes four weeks of semaglutide medication, ongoing provider care and support, metabolic lab testing every six months, essential supplies, wellness coaching, and full platform access with educational content.” (Read 2026-10-07.)
Is Enhance.MD available in my state?
40 of 51. Not available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina, Tennessee, West Virginia.
Alternatives to Enhance.MD
Yucca Health
7.5from $125/mo on a $750 prepaid 6-month plan · compounded semaglutide, compounded tirzepatide
Luvo Health
7.5from $209/4 weeks (billed every 28 days) · compounded semaglutide, compounded tirzepatide
Trimi
7.5from $99/mo on a 12-month plan, $1,188 billed upfront · compounded semaglutide, compounded tirzepatide
Mochi Health
7.5from $49/mo membership on a $588 prepaid year, medication billed separately · compounded semaglutide, compounded tirzepatide
Telos Rx
7.6from $99/mo on its lowest-priced plan length ("Your price depends on plan length"; the lengths are not listed) · compounded semaglutide, compounded tirzepatide
Nu Image Medical
7.4from $89/mo on a 6-month supply · compounded semaglutide injection, compounded semaglutide rapid-dissolve tablets
Care Bare Rx
7.6from $199/mo, plan length not stated · compounded semaglutide, compounded tirzepatide
yourEra
7.4from $73/mo, "as low as" on its homepage, which doesn't state the plan length · compounded semaglutide, compounded tirzepatide
Welludr (formerly Wellmedr)
7.6from $49/mo on a monthly plan at a Fall sale price, shipped every 4 weeks · compounded semaglutide, compounded tirzepatide
RxSpan MD
7.3from $175/mo on a $2,094 upfront 12-month plan · compounded semaglutide, compounded tirzepatide
bmiMD
7.6from $119/mo on a $1,428 prepaid year · compounded semaglutide, compounded tirzepatide
Shed
7.3from $159/mo on a 12-month plan paid upfront ($199 month to month) · compounded semaglutide, compounded tirzepatide
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Alexandru Vieru · Founder & Editor
Alexandru Vieru founded and edits MyGLP1 Guides, and personally re-checks every price, medication list and refund policy the site publishes before it goes live. That's what feeds the site's 4-criteria, 1-to-10 rubric. He holds no medical license, so any clinical fact on this site traces back to something citable (an FDA page, a manufacturer's own label, a peer-reviewed paper), never his own judgment.
Price status: Verified 2026-10-05.Scores are derived from our documented methodology and are never influenced by affiliate commissions. “Pick the program” links may be affiliate links that support our work. Educational information only. Not medical advice.