GMy GLP-1 Guides

Trimi vs Enhance.MD: Which GLP-1 Clinic Is Better in 2026?

✓ 53 clinics scored independently✓ Prices checked weekly✓ Scores from evidence · partners first at equal scores

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Short answer

Trimi and Enhance.MD tie at 7.5/10, so it comes down to price and transparency. Trimi is cheaper at $99/mo on a 12-month plan, $1,188 billed upfront.

Tied: Trimi vs Enhance.MD

Trimi and Enhance.MD are tied at 7.5/10.

Winner
#12 of 53

Trimi

7.5

An all-inclusive compounded GLP-1 plan that prints every billing term with its full charge and names its clinicians and pharmacy, from $99 a month on a year paid up front. Trustpilot has suspended its rating after removing fake reviews.

from $99/mo on a 12-month plan, $1,188 billed upfront

Visit Trimi
#14 of 53

Enhance.MD

7.5

One of the few clinics here that names its actual pharmacies and medical groups, publishes every plan length with its billing cadence, and bundles metabolic lab work every six months. But it's priced at the top of this set and it doesn't ship to 11 states.

from $212/mo, billed every 48 weeks

Visit Enhance.MD

Trimi vs Enhance.MD, side by side

FeatureTrimiEnhance.MD
Our score7.5/107.5/10
Starting price$99/mo on a 12-month plan, $1,188 billed upfront$212/mo, billed every 48 weeks
Medication typescompounded semaglutide, compounded tirzepatidecompounded semaglutide, compounded tirzepatide, compounded semaglutide + tirzepatide, microdosing
Best for——
Overall ranking#12#14
Price & Value (25%)7.56.0
Clinical Oversight (30%)8.08.0
Medication Options (20%)7.58.0
Transparency (25%)7.08.0

Sources: Trimi pricing verified on trytrimi.com, Enhance.MD pricing verified on enhance.md

Pros & cons

Trimi

Pros

  • + Publishes all four billing terms for both medications with the amount charged, from $175 month to month to $1,188 for a year of semaglutide, and the price does not rise with the dose
  • + Names its medical group (Arora Health), two physicians in clinical leadership and its pharmacy with a licence number (BelieveRx, Texas #35264)
  • + Medication, supplies, provider care and overnight shipping in one price, refunded in full if a provider does not prescribe

Cons

  • − Weaker on Transparency (7.0/10)
  • − Weaker on Price & Value (7.5/10)
  • − Weaker on Medication Options (7.5/10)

Enhance.MD

Pros

  • + Publishes the full price grid (all four plan lengths, each with its billing cadence) plus the same price at every dose
  • + Names all three partner pharmacies and both medical groups on its own site, which almost nobody in this category does
  • + Metabolic lab testing every 6 months and ongoing provider care included in the monthly price, no separate membership fee

Cons

  • − Not available in 11 states
  • − Weaker on Price & Value (6.0/10)
  • − Weaker on Clinical Oversight (8.0/10)

The bottom line

After scoring all 53 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), Trimi and Enhance.MD are tied at 7.5/10. There is no clear overall winner here, so the right choice comes down to what matters most to you.

Choose Trimi if you want this option. From $99/mo on a 12-month plan, $1,188 billed upfront.

Visit Trimi →

Choose Enhance.MD if you want this option. From $212/mo, billed every 48 weeks.

Visit Enhance.MD →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →

Ready to start GLP-1 weight loss?

Trimi and Enhance.MD are tied on score. Either is a solid choice.

Frequently asked questions

Which is better, Trimi or Enhance.MD?

Trimi and Enhance.MD are tied at 7.5/10. There's no clear overall winner. If price is the deciding factor, Trimi starts at $99/mo on a 12-month plan, $1,188 billed upfront.

How much does Trimi cost vs Enhance.MD?

Trimi is from $99/mo on a 12-month plan, $1,188 billed upfront and Enhance.MD is from $212/mo, billed every 48 weeks. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.

What is the difference between Trimi and Enhance.MD?

Trimi (7.5/10, #12 of 53) and Enhance.MD (7.5/10, #14 of 53) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.

Does Trimi or Enhance.MD take insurance?

Neither Trimi nor Enhance.MD typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

Wellorithm vs Trimi→Wellorithm vs Enhance.MD→Lavender Sky Health vs Trimi→Lavender Sky Health vs Enhance.MD→HealthRX vs Trimi→HealthRX vs Enhance.MD→

Top picks

Wellorithm

7.9

from $247/mo from month 2 ($147 first month)

Lavender Sky Health

7.9

from $78/mo equivalent on an 8 to 10 week supply

HealthRX

7.8

from $99/mo on a $1,188 prepaid year

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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Pick the program” links may be affiliate links that support our work. Educational information only. Not medical advice.