Sesame vs Trimi: Which GLP-1 Clinic Is Better in 2026?
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Short answer
Sesame and Trimi tie at 7.5/10, so it comes down to medication options.
Sesame and Trimi are tied at 7.5/10.
Sesame · from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately
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SSesame
A clinician marketplace for brand-name GLP-1s: you choose the provider, pay a care fee from $59/mo on a 12-month plan billed once, and buy the medication separately, from $149/mo for the Wegovy pill or Foundayo.
from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately
Visit →Is Sesame legit?
An all-inclusive compounded GLP-1 plan that prints every billing term with its full charge and names its clinicians and pharmacy, from $99 a month on a year paid up front. Trustpilot has suspended its rating after removing fake reviews.
from $99/mo on a 12-month plan, $1,188 billed upfront
Read Review →Sesame vs Trimi, side by side
| Feature | Sesame | Trimi |
|---|---|---|
| Our score | 7.5/10 | 7.5/10 |
| Starting price | $59/mo care fee on a 12-month plan billed once ($708), medication billed separately | $99/mo on a 12-month plan, $1,188 billed upfront |
| Medication types | Wegovy, Wegovy Pill, Zepbound, Foundayo | compounded semaglutide, compounded tirzepatide |
| Best for | — | — |
| Overall ranking | #14 | #15 |
| Price & Value (25%) | not scored (counted at 7.0) | 7.5 |
| Clinical Oversight (30%) | 8.0 | 8.0 |
| Medication Options (20%) | 8.0 | 7.5 |
| Transparency (25%) | 7.0 | 7.0 |
Sources: Sesame pricing verified on sesamecare.com, Trimi pricing verified on trytrimi.com
Pros & cons
Sesame
Pros
- + Says next to the price that medication is paid separately, gives a floor for it, and prints the price of each medication on the same page
- + You choose your provider from named clinicians, with video visits, messaging and labs at Quest included in the care fee (except in nine states)
- + Brand-name Wegovy (pen and pill), Zepbound and Foundayo, picked up the same day at your pharmacy or delivered
- + Publishes its refund and cancellation terms and the billing schedule of every plan
Cons
Trimi
Pros
- + Publishes all four billing terms for both medications with the amount charged, from $175 month to month to $1,188 for a year of semaglutide, and the price does not rise with the dose
- + Names its medical group (Arora Health), two physicians in clinical leadership and its pharmacy with a licence number (BelieveRx, Texas #35264)
- + Medication, supplies, provider care and overnight shipping in one price, refunded in full if a provider does not prescribe
Cons
- − Weaker on Medication Options (7.5/10 vs 8.0)
The bottom line
After scoring all 61 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), Sesame and Trimi are tied at 7.5/10. There is no clear overall winner here, so the right choice comes down to what matters most to you.
Sesame. From $59/mo care fee on a 12-month plan billed once ($708), medication billed separately.
Visit →Trimi. From $99/mo on a 12-month plan, $1,188 billed upfront.
Read Review →Editor's overall pick
Not sold on either? Our highest-rated partner clinic outside this pair is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →
Ready to start GLP-1 weight loss?
Sesame and Trimi are tied on score.
Frequently asked questions
Which is better, Sesame or Trimi?
Sesame and Trimi are tied at 7.5/10. There's no clear overall winner.
How much does Sesame cost vs Trimi?
Sesame is from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately and Trimi is from $99/mo on a 12-month plan, $1,188 billed upfront. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Sesame and Trimi?
Sesame (7.5/10, #14 of 61) and Trimi (7.5/10, #15 of 61) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Sesame or Trimi take insurance?
Insurance terms differ by clinic and by drug: some clinics are cash-pay only, and some help with insurance for brand-name drugs. Each clinic's review says what it publishes. HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.