Yucca Health vs Sesame Care: Which GLP-1 Clinic Is Better in 2026?
Yucca Health wins overall, scoring 7.8/10 vs 7.2/10. If price is your priority, Sesame Care is cheaper at $99/mo.
Yucca Health
A clean, value-first option: compounded semaglutide from $146/mo, free 2-day shipping and a LegitScript-certified pharmacy behind it — both GLP-1 injectables, nationwide.
from $146/mo
Visit Yucca HealthSesame Care
A pay-per-visit telehealth marketplace rather than a subscription clinic — a $99/28-day membership covers ongoing care, with compounded semaglutide available from around $249/mo and brand-name Wegovy options through partner pharmacies.
from $99/mo
Visit Sesame CareYucca Health vs Sesame Care, side by side
| Feature | Yucca Health | Sesame Care |
|---|---|---|
| Our score | 7.8/10 | 7.2/10 |
| Starting price | $146/mo | $99/mo |
| Medication types | compounded semaglutide, compounded tirzepatide | compounded semaglutide, brand-name semaglutide (Wegovy) |
| Best for | Best Value | — |
| Overall ranking | #6 | #18 |
| Price & Value (25%) | 8.0 | 7.0 |
| Clinical Oversight (25%) | 8.0 | 7.0 |
| Medication Options (20%) | 7.5 | 7.5 |
| User Experience (15%) | 8.0 | 7.5 |
| Transparency (15%) | 7.0 | 7.0 |
Pros & cons
Yucca Health
Pros
- + Low $146/mo entry on a 6-month semaglutide plan
- + Free UPS 2-Day Air, kit included, 24/7 care team
- + LegitScript-certified, licensed-provider review in ~24h
Cons
- − Weaker on Transparency (7.0/10)
- − Weaker on Medication Options (7.5/10)
- − Weaker on Price & Value (8.0/10)
Sesame Care
Pros
- + Marketplace model: pay for care access ($99/28 days) without a long-term program lock-in
- + Offers both compounded and brand-name Wegovy paths
- + Backed by a large, well-funded telehealth marketplace with broad physician network
Cons
- − Weaker on Price & Value (7.0/10)
- − Weaker on Clinical Oversight (7.0/10)
- − Weaker on Transparency (7.0/10)
The bottom line
After scoring all 22 clinics on price, clinical oversight, medication options, experience and transparency, Yucca Health (7.8/10) comes out ahead of Sesame Care (7.2/10) — but the right choice depends on what matters most to you.
Choose Yucca Health if you want best value — from $146/mo.
Visit Yucca Health →Choose Sesame Care if you want this option — from $99/mo.
Visit Sesame Care →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Gala Health (8.3/10) from $149/mo — read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is Yucca Health.
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How we score: every clinic is rated on five weighted criteria from documented evidence, re-verified monthly. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.