Wellorithm vs Sesame: Which GLP-1 Clinic Is Better in 2026?
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Short answer
Wellorithm wins overall, scoring 7.9/10 vs 7.5/10. Mainly on medication options and transparency.
Wellorithm wins overall, scoring 7.9/10 vs 7.5/10.
Wellorithm · $247/mo from month 2 ($147 first month)
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Compounded GLP-1 (semaglutide and tirzepatide, injection or oral) and real brand-name Wegovy, Ozempic, Mounjaro and Zepbound on one account. $247/mo after a $147 first month, with board-certified obesity specialists and 24/7 support.
$247/mo from month 2 ($147 first month)
Visit →SSesame
A clinician marketplace for brand-name GLP-1s: you choose the provider, pay a care fee from $59/mo on a 12-month plan billed once, and buy the medication separately, from $149/mo for the Wegovy pill or Foundayo.
from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately
Visit →Is Sesame legit?Wellorithm vs Sesame, side by side
| Feature | Wellorithm | Sesame |
|---|---|---|
| Our score | 7.9/10 | 7.5/10 |
| Starting price | $247/mo from month 2 ($147 first month) | $59/mo care fee on a 12-month plan billed once ($708), medication billed separately |
| Medication types | compounded semaglutide, compounded tirzepatide, oral, brand-name Wegovy/Ozempic/Mounjaro/Zepbound | Wegovy, Wegovy Pill, Zepbound, Foundayo |
| Best for | Brand-name GLP-1 access | — |
| Overall ranking | #1 | #14 |
| Price & Value (25%) | 6.5 | not scored (counted at 7.0) |
| Clinical Oversight (30%) | 8.0 | 8.0 |
| Medication Options (20%) | 9.5 | 8.0 |
| Transparency (25%) | 8.0 | 7.0 |
Sources: Wellorithm pricing verified on glp.wellorithm.com, Sesame pricing verified on sesamecare.com
Pros & cons
Wellorithm
Pros
- + Brand-name Wegovy/Ozempic/Mounjaro/Zepbound plus low-cost compounded options
- + Compounded semaglutide $147 for the first month, then $247/mo, free expedited shipping
- + Board-certified obesity specialists and 24/7 support
Cons
Sesame
Pros
- + Says next to the price that medication is paid separately, gives a floor for it, and prints the price of each medication on the same page
- + You choose your provider from named clinicians, with video visits, messaging and labs at Quest included in the care fee (except in nine states)
- + Brand-name Wegovy (pen and pill), Zepbound and Foundayo, picked up the same day at your pharmacy or delivered
- + Publishes its refund and cancellation terms and the billing schedule of every plan
Cons
- − Weaker on Medication Options (8.0/10 vs 9.5)
- − Weaker on Transparency (7.0/10 vs 8.0)
The bottom line
After scoring all 61 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), Wellorithm (7.9/10) comes out ahead of Sesame (7.5/10). But the right choice still depends on what matters most to you.
Choose Wellorithm if you want brand-name GLP-1 access. $247/mo from month 2 ($147 first month).
Visit →Sesame. From $59/mo care fee on a 12-month plan billed once ($708), medication billed separately.
Visit →Editor's overall pick
Not sold on either? Our highest-rated partner clinic outside this pair is HealthRX (7.8/10) from $97/mo, 12-mo plan. Read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is Wellorithm.
Frequently asked questions
Which is better, Wellorithm or Sesame?
Wellorithm scores higher overall (7.9/10 vs 7.5/10) and is our recommended pick for most people.
How much does Wellorithm cost vs Sesame?
Wellorithm is $247/mo from month 2 ($147 first month) and Sesame is from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Wellorithm and Sesame?
Wellorithm (7.9/10, #1 of 61) and Sesame (7.5/10, #14 of 61) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Wellorithm or Sesame take insurance?
Insurance terms differ by clinic and by drug: some clinics are cash-pay only, and some help with insurance for brand-name drugs. Each clinic's review says what it publishes. HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.