GMy GLP-1 Guides

Sesame vs Henry Meds: Which GLP-1 Clinic Is Better in 2026?

Short answer

Sesame is the better pick: it scores 7.5/10 against 7.0/10 for Henry Meds, mainly on transparency and clinical oversight. Sesame costs $59/mo care fee on a 12-month plan billed once ($708), medication billed separately; Henry Meds costs $119/mo on a $1,428 prepaid year.

Sesame · from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately

✓ 61 clinics scored independently✓ Prices checked weekly✓ Scores from evidence · partners first at equal scores

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Our pick: Sesame

Sesame wins overall, scoring 7.5/10 vs 7.0/10.

Sesame · from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately

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Winner
#14 of 61

SSesame

7.5

A clinician marketplace for brand-name GLP-1s: you choose the provider, pay a care fee from $59/mo on a 12-month plan billed once, and buy the medication separately, from $149/mo for the Wegovy pill or Foundayo.

from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately

Visit →Is Sesame legit?
#39 of 61

Henry MedsHenry Meds

7.0

Publishes a full plan grid with 6- and 12-month totals and a named medical team, with 12,531 Trustpilot reviews at 4.4, but its own pages quote three different prices for the same drugs, it names no pharmacy and no medical group, and BBB rates it F with 234 complaints closed in three years.

from $119/mo on a $1,428 prepaid year

Read Review →

Sesame vs Henry Meds, side by side

FeatureSesameHenry Meds
Our score7.5/107.0/10
Starting price$59/mo care fee on a 12-month plan billed once ($708), medication billed separately$119/mo on a $1,428 prepaid year
Medication typesWegovy, Wegovy Pill, Zepbound, Foundayocompounded semaglutide, compounded liraglutide, oral semaglutide tablets, sublingual semaglutide drops, oral tirzepatide tablets
Best for——
Overall ranking#14#39
Price & Value (25%)not scored (counted at 7.0)7.0
Clinical Oversight (30%)8.07.5
Medication Options (20%)8.08.5
Transparency (25%)7.05.0

Sources: Sesame pricing verified on sesamecare.com, Henry Meds pricing verified on henrymeds.com

Sesame vs Henry Meds: what a year costs

Sesame: no verified non-sale 12-month semaglutide cost with a documented billing period is recorded.

Sesame: no verified non-sale 12-month tirzepatide cost with a documented billing period is recorded.

Henry Meds: no verified non-sale 12-month tirzepatide cost with a documented billing period is recorded.

Sesame: no 12-month total, because the care fee and the medication are billed separately, and the Wegovy pill rises from $149 to $299 a month at the 9 mg and 25 mg doses.

To get started, Henry Meds asks for $297 (first payment, $297 a month); Sesame publishes no first-month price we can set against it.

Sources: henrymeds.com, read October 25, 2026.

Which states Sesame and Henry Meds treat

Sesame and Henry Meds publish no list of states, so you have to check yours at the start of intake.

Sources: sesamecare.com, read November 4, 2026; henrymeds.com, read October 25, 2026.

Medications and doses: Sesame vs Henry Meds

Sesame and Henry Meds have no medication in common: Sesame lists Wegovy pen, Wegovy pill (oral semaglutide), Zepbound vial or KwikPen and Foundayo (orforglipron) pill, and Henry Meds lists compounded semaglutide injection, compounded oral semaglutide (drops or tablets), compounded oral tirzepatide, compounded liraglutide and microdose compounded semaglutide.

Sources: sesamecare.com, read November 4, 2026; sesamecare.com, read November 4, 2026; henrymeds.com, read October 25, 2026; henrymeds.com, read October 25, 2026.

Labs, fees and what Sesame and Henry Meds include

Sesame bills a $99 monthly fee separately from the medication; Henry Meds' plan prices include the medication.

Neither Sesame nor Henry Meds says whether labs are required or what they cost.

Sources: sesamecare.com, read November 4, 2026; henrymeds.com, read October 25, 2026; henrymeds.com, read October 25, 2026.

Cancelling and refunds: Sesame vs Henry Meds

To stop the next charge, Henry Meds needs 2 days' notice; Sesame states no notice period.

Sources: sesamecare.com, read November 4, 2026; henrymeds.com, read October 25, 2026; henrymeds.com, read October 25, 2026.

FDA warning letters: Sesame and Henry Meds

Neither Sesame nor Henry Meds appears as the recipient of an FDA warning letter in FDA's database, searched November 4, 2026.

We searched FDA's database for "Sesame" (Sesame) and "Henry Meds" (Henry Meds).

Sources: fda.gov, read November 4, 2026; fda.gov, read October 25, 2026.

Independent review data: Sesame vs Henry Meds

Sesame and Henry Meds rate within a few tenths of each other on Trustpilot (4.5 from 4,402 reviews, and 4.4 from 12,531).

The Better Business Bureau rates Sesame A+, and Henry Meds F, 234 complaints closed in 3 years.

Sources: trustpilot.com, read August 30, 2026; bbb.org, read October 12, 2026; trustpilot.com, read October 4, 2026; bbb.org, read October 4, 2026.

Who each one suits

Sesame suits you if

  • you want Wegovy pen, Wegovy pill (oral semaglutide), Zepbound vial or KwikPen and Foundayo (orforglipron) pill.

Henry Meds suits you if

  • you want compounded semaglutide injection, compounded oral semaglutide (drops or tablets), compounded oral tirzepatide, compounded liraglutide and microdose compounded semaglutide.
  • you want one price that includes the medication, with no separate $99 monthly fee.

Verdict from the data

Sesame leads on none of the facts above. Henry Meds comes out ahead on medication choice and an all-in price.

Pick Henry Meds if medication choice and an all-in price matter most to you. For everyone else our overall pick is Sesame (7.5/10 against 7.0), a score that also weighs clinical oversight and transparency.

Pros & cons

Sesame

Pros

  • + Says next to the price that medication is paid separately, gives a floor for it, and prints the price of each medication on the same page
  • + You choose your provider from named clinicians, with video visits, messaging and labs at Quest included in the care fee (except in nine states)
  • + Brand-name Wegovy (pen and pill), Zepbound and Foundayo, picked up the same day at your pharmacy or delivered
  • + Publishes its refund and cancellation terms and the billing schedule of every plan

Cons

  • − Weaker on Medication Options (8.0/10 vs 8.5)

Henry Meds

Pros

  • + Month-to-month from $179/mo with provider visits, medication, supplies and shipping included, and cancellation online, by email or by phone
  • + Three GLP-1 molecules (semaglutide, liraglutide, tirzepatide) across injections, dissolving tablets and sublingual drops
  • + A large, current review record: 4.4 on Trustpilot across 12,531 reviews, 461 of them in the last 12 months

Cons

  • − Weaker on Transparency (5.0/10 vs 7.0)
  • − Weaker on Clinical Oversight (7.5/10 vs 8.0)

The bottom line

After scoring all 61 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), Sesame (7.5/10) comes out ahead of Henry Meds (7.0/10). But the right choice still depends on what matters most to you.

Sesame. From $59/mo care fee on a 12-month plan billed once ($708), medication billed separately.

Visit →

Henry Meds. From $119/mo on a $1,428 prepaid year.

Read Review →

Editor's overall pick

Not sold on either? Our highest-rated partner clinic outside this pair is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →

Ready to start GLP-1 weight loss?

Our verdict for this matchup is Sesame.

Sesame · from $59/mo care fee on a 12-month plan billed once ($708), medication billed separatelyVisit →
Henry MedsRead Review →
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Frequently asked questions

Which is better, Sesame or Henry Meds?

Sesame scores higher overall (7.5/10 vs 7.0/10) and is our recommended pick for most people.

How much does Sesame cost vs Henry Meds?

Sesame is from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately and Henry Meds is from $119/mo on a $1,428 prepaid year. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.

What is the difference between Sesame and Henry Meds?

Sesame (7.5/10, #14 of 61) and Henry Meds (7.0/10, #39 of 61) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.

Does Sesame or Henry Meds take insurance?

Insurance terms differ by clinic and by drug: some clinics are cash-pay only, and some help with insurance for brand-name drugs. Each clinic's review says what it publishes. HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

Wellorithm vs Sesame→Wellorithm vs Henry Meds→Lavender Sky Health vs Sesame→Lavender Sky Health vs Henry Meds→Yucca Health vs Sesame→Yucca Health vs Henry Meds→

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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.