Sesame vs Ro: Which GLP-1 Clinic Is Better in 2026?
Short answer
Ro (Body by Ro) scores higher overall: 7.7/10 against 7.5/10 for Sesame, mainly on clinical oversight. Sesame costs $59/mo care fee on a 12-month plan billed once ($708), medication billed separately; Ro (Body by Ro) costs $74/mo membership on a plan prepaid annually, medication billed separately.
Sesame · from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately
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A brand-name GLP-1 service that publishes both of its bills: a Ro Body membership from $74/mo on a plan prepaid annually, and medication at the manufacturer's self-pay price from $149/mo. It is rated A+ and accredited by BBB, and its terms make the paid membership fee non-refundable.
from $74/mo membership on a plan prepaid annually, medication billed separately
Read Review →SSesame
A clinician marketplace for brand-name GLP-1s: you choose the provider, pay a care fee from $59/mo on a 12-month plan billed once, and buy the medication separately, from $149/mo for the Wegovy pill or Foundayo.
from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately
Visit →Is Sesame legit?Ro (Body by Ro) vs Sesame, side by side
| Feature | Ro (Body by Ro) | Sesame |
|---|---|---|
| Our score | 7.7/10 | 7.5/10 |
| Starting price | $74/mo membership on a plan prepaid annually, medication billed separately | $59/mo care fee on a 12-month plan billed once ($708), medication billed separately |
| Medication types | Wegovy, Wegovy Pill, Zepbound, Foundayo, Ozempic | Wegovy, Wegovy Pill, Zepbound, Foundayo |
| Best for | — | — |
| Overall ranking | #8 | #14 |
| Price & Value (25%) | not scored (counted at 7.0) | not scored (counted at 7.0) |
| Clinical Oversight (30%) | 8.5 | 8.0 |
| Medication Options (20%) | 8.0 | 8.0 |
| Transparency (25%) | 7.0 | 7.0 |
Sources: Ro (Body by Ro) pricing verified on ro.co, Sesame pricing verified on sesamecare.com
Ro (Body by Ro) vs Sesame: what a year costs
Ro (Body by Ro): no verified non-sale 12-month semaglutide cost with a documented billing period is recorded.
Sesame: no verified non-sale 12-month semaglutide cost with a documented billing period is recorded.
Ro (Body by Ro): no verified non-sale 12-month tirzepatide cost with a documented billing period is recorded.
Sesame: no verified non-sale 12-month tirzepatide cost with a documented billing period is recorded.
Sesame: no 12-month total, because the care fee and the medication are billed separately, and the Wegovy pill rises from $149 to $299 a month at the 9 mg and 25 mg doses.
Sources: ro.co, read October 25, 2026.
Which states Ro (Body by Ro) and Sesame treat
Ro (Body by Ro) and Sesame publish no list of states, so you have to check yours at the start of intake.
Sources: ro.co, read October 25, 2026; sesamecare.com, read November 4, 2026.
Medications and doses: Ro (Body by Ro) vs Sesame
Both list Wegovy pill (oral semaglutide), Wegovy pen, Zepbound KwikPen and Foundayo (orforglipron) pill.
Only Ro (Body by Ro) lists Ozempic.
For Zepbound KwikPen, only Ro (Body by Ro) publishes doses (2.5, 5, 7.5, 10, 12.5 and 15 mg).
For Foundayo (orforglipron) pill, only Ro (Body by Ro) publishes doses (0.8, 2.5, 5.5, 9, 14.5 and 17.2 mg).
Sources: ro.co, read October 25, 2026; ro.co, read October 25, 2026; sesamecare.com, read November 4, 2026; sesamecare.com, read November 4, 2026.
Labs, fees and what Ro (Body by Ro) and Sesame include
Both bill a separate monthly fee on top of medication: $149 at Ro (Body by Ro), $99 at Sesame.
Ro (Body by Ro) asks for labs only when the clinician needs them, and covers them; Sesame does not say whether labs are required.
Sources: ro.co, read October 25, 2026; sesamecare.com, read November 4, 2026; ro.co, read October 25, 2026.
Cancelling and refunds: Ro (Body by Ro) vs Sesame
To stop the next charge, Ro (Body by Ro) needs 2 days' notice; Sesame states no notice period.
If you are turned down, or cancel before a prescription is written, Ro (Body by Ro) gives a partial refund; Sesame's pages do not say.
Sources: ro.co, read October 25, 2026; sesamecare.com, read November 4, 2026.
FDA warning letters: Ro (Body by Ro) and Sesame
Neither Ro (Body by Ro) nor Sesame appears as the recipient of an FDA warning letter in FDA's database, searched October 25, 2026.
We searched FDA's database for "Roman Health" and "Ro Health" (Ro (Body by Ro)) and "Sesame" (Sesame).
Sources: fda.gov, read October 25, 2026; fda.gov, read November 4, 2026.
Independent review data: Ro (Body by Ro) vs Sesame
On Trustpilot, Sesame rates 4.5 from 4,402 reviews, against 3.9 from 7,150 for Ro (Body by Ro).
Better Business Bureau: Ro (Body by Ro), rated A+ (read October 14, 2026); Sesame, rated A+ (read October 12, 2026).
Sources: trustpilot.com, read October 14, 2026; bbb.org, read October 14, 2026; trustpilot.com, read August 30, 2026; bbb.org, read October 12, 2026.
Who each one suits
Ro (Body by Ro) suits you if
- you want Ozempic.
Sesame suits you if
- you weigh customer ratings (Trustpilot 4.5 against 3.9).
Verdict from the data
Ro (Body by Ro) comes out ahead on medication choice. Sesame comes out ahead on customer ratings.
Pick Sesame if customer ratings matters most to you. For everyone else our overall pick is Ro (Body by Ro) (7.7/10 against 7.5), a score that also weighs clinical oversight and transparency.
Pros & cons
Ro (Body by Ro)
Pros
- + Publishes all four membership plan lengths ($74, $89, $99 and $149 a month) and the starting medication price for each drug before any intake, under the heading "Two separate charges"
- + Names its own pharmacy (Roman Health Pharmacy LLC) in its terms, with care from affiliated physician practices and ongoing check-ins, provider messaging and dose adjustments described as part of the membership
- + Brand-name Wegovy® (pen and pill), Zepbound®, Foundayo® and Ozempic®, with a free insurance check and prior-authorization help for the pens
Cons
Sesame
Pros
- + Says next to the price that medication is paid separately, gives a floor for it, and prints the price of each medication on the same page
- + You choose your provider from named clinicians, with video visits, messaging and labs at Quest included in the care fee (except in nine states)
- + Brand-name Wegovy (pen and pill), Zepbound and Foundayo, picked up the same day at your pharmacy or delivered
- + Publishes its refund and cancellation terms and the billing schedule of every plan
Cons
- − Weaker on Clinical Oversight (8.0/10 vs 8.5)
The bottom line
After scoring all 61 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), Ro (Body by Ro) (7.7/10) comes out ahead of Sesame (7.5/10). But the right choice still depends on what matters most to you.
Ro (Body by Ro). From $74/mo membership on a plan prepaid annually, medication billed separately.
Read Review →Sesame. From $59/mo care fee on a 12-month plan billed once ($708), medication billed separately.
Visit →Editor's overall pick
Not sold on either? Our highest-rated partner clinic outside this pair is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →
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Ro (Body by Ro) scores higher on our rubric. It is not one of our partners.
Frequently asked questions
Which is better, Ro (Body by Ro) or Sesame?
Ro (Body by Ro) scores higher overall (7.7/10 vs 7.5/10) on our rubric.
How much does Ro (Body by Ro) cost vs Sesame?
Ro (Body by Ro) is from $74/mo membership on a plan prepaid annually, medication billed separately and Sesame is from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Ro (Body by Ro) and Sesame?
Ro (Body by Ro) (7.7/10, #8 of 61) and Sesame (7.5/10, #14 of 61) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Ro (Body by Ro) or Sesame take insurance?
Insurance terms differ by clinic and by drug: some clinics are cash-pay only, and some help with insurance for brand-name drugs. Each clinic's review says what it publishes. HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.