Telos Rx vs Sesame Care: Which GLP-1 Clinic Is Better in 2026?
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Short answer
Telos Rx wins overall, scoring 7.6/10 vs 7.1/10 — mainly on price & value and medication options.
Telos Rx wins overall, scoring 7.6/10 vs 7.1/10.
Telos Rx
Flat $99/mo compounded semaglutide with no membership fee and no long-term commitment — cancel anytime — plus a genuine oral (needle-free) route for both semaglutide and tirzepatide, which most budget clinics in this range don't offer.
from $99/mo
Visit Telos RxSesame Care
A pay-per-visit telehealth marketplace rather than a subscription clinic — a $99/28-day membership covers ongoing care, with compounded semaglutide available from around $249/mo and brand-name Wegovy options through partner pharmacies.
from $99/mo
Visit Sesame CareTelos Rx vs Sesame Care, side by side
| Feature | Telos Rx | Sesame Care |
|---|---|---|
| Our score | 7.6/10 | 7.1/10 |
| Starting price | $99/mo | $99/mo |
| Medication types | compounded semaglutide, compounded tirzepatide, oral, microdosing | compounded semaglutide, brand-name semaglutide (Wegovy) |
| Best for | — | — |
| Overall ranking | #12 | #24 |
| Price & Value (25%) | 8.0 | 7.0 |
| Clinical Oversight (30%) | 7.0 | 7.0 |
| Medication Options (20%) | 8.5 | 7.5 |
| Transparency (25%) | 7.0 | 7.0 |
Sources: Telos Rx pricing verified on telosrx.com
Pros & cons
Telos Rx
Pros
- + Compounded semaglutide from $99/mo, tirzepatide from $139/mo — all-inclusive (visit, shipping, dose changes, support all $0)
- + Cancel anytime, no penalties — no 6- or 12-month prepay commitment required for the advertised price
- + Injectable AND oral (needle-free) routes for both semaglutide and tirzepatide, plus a lower-cost microdosing tier
Cons
- − Weaker on Clinical Oversight (7.0/10)
- − Weaker on Transparency (7.0/10)
- − Weaker on Price & Value (8.0/10)
Sesame Care
Pros
- + Marketplace model: pay for care access ($99/28 days) without a long-term program lock-in
- + Offers both compounded and brand-name Wegovy paths
- + Backed by a large, well-funded telehealth marketplace with broad physician network
Cons
- − Weaker on Price & Value (7.0/10)
- − Weaker on Clinical Oversight (7.0/10)
- − Weaker on Transparency (7.0/10)
The bottom line
After scoring all 37 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), Telos Rx (7.6/10) comes out ahead of Sesame Care (7.1/10) — but the right choice still depends on what matters most to you.
Choose Telos Rx if you want this option — from $99/mo.
Visit Telos Rx →Choose Sesame Care if you want this option — from $99/mo.
Visit Sesame Care →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Wellorithm (8.3/10) from $147/mo — read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is Telos Rx.
Frequently asked questions
Which is better, Telos Rx or Sesame Care?
Telos Rx scores higher overall (7.6/10 vs 7.1/10) and is our recommended pick for most people. Telos Rx also has the lower starting price at $99/mo.
How much does Telos Rx cost vs Sesame Care?
Telos Rx is from $99/mo and Sesame Care is from $99/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Telos Rx and Sesame Care?
Telos Rx (7.6/10, #12 of 37) and Sesame Care (7.1/10, #24 of 37) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Telos Rx or Sesame Care take insurance?
Neither Telos Rx nor Sesame Care typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.