TrimRx vs MangoRx: Which GLP-1 Clinic Is Better in 2026?
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Short answer
TrimRx wins overall, scoring 5.8/10 vs 5.5/10. Mainly on transparency and medication options.
TrimRx wins overall, scoring 5.8/10 vs 5.5/10.
A cash-pay compounded GLP-1 service that bundles the consult, medication and shipping into one package price. The price rises from $199 to $299 after the first month, BBB rates it F with a pattern-of-complaints alert, and it names neither its pharmacy nor its medical group.
from $299/follow-up package after a $199 first month (billing period not stated)
Visit TrimRx
A needle-free, oral-only route, compounded semaglutide and tirzepatide as dissolvable tablets, but premium-priced at $299/mo, with active Eli Lilly litigation and trust gaps that hold it back.
from $299/mo (shipped monthly; plan length not stated)
Pick the program →TrimRx vs MangoRx, side by side
| Feature | TrimRx | MangoRx |
|---|---|---|
| Our score | 5.8/10 | 5.5/10 |
| Starting price | $299/follow-up package after a $199 first month (billing period not stated) | $299/mo (shipped monthly; plan length not stated) |
| Medication types | compounded GLP-1 (molecule not named), compounded tirzepatide | oral semaglutide, oral tirzepatide |
| Best for | — | — |
| Overall ranking | #52 | #53 |
| Price & Value (25%) | 5.5 | 5.5 |
| Clinical Oversight (30%) | 6.0 | 6.0 |
| Medication Options (20%) | 7.0 | 6.5 |
| Transparency (25%) | 5.0 | 4.0 |
Sources: TrimRx pricing verified on trimrx.com, MangoRx pricing verified on mangorx.com
Pros & cons
TrimRx
Pros
- + One package price covers the telehealth consult, the medication if prescribed, shipping and ongoing support, with no separate membership fee
- + Its Terms state plainly that a compounded drug is not a generic and that TrimRx claims no equivalence with an FDA-approved drug
- + Serves all 50 states and needs no insurance
Cons
- − Weaker on Transparency (5.0/10)
- − Weaker on Price & Value (5.5/10)
- − Weaker on Clinical Oversight (6.0/10)
MangoRx
Pros
- + Fully needle-free: oral dissolvable semaglutide & tirzepatide
- + Physician-reviewed prescriptions, B6 to ease nausea
- + Discreet shipping from a US compounding pharmacy
Cons
- − Not available in 12 states
- − Weaker on Transparency (4.0/10)
- − Weaker on Price & Value (5.5/10)
The bottom line
After scoring all 53 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), TrimRx (5.8/10) comes out ahead of MangoRx (5.5/10). But the right choice still depends on what matters most to you.
Choose TrimRx if you want this option. From $299/follow-up package after a $199 first month (billing period not stated).
Visit TrimRx →Choose MangoRx if you want this option. From $299/mo (shipped monthly; plan length not stated).
Pick the program →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is TrimRx.
Frequently asked questions
Which is better, TrimRx or MangoRx?
TrimRx scores higher overall (5.8/10 vs 5.5/10) and is our recommended pick for most people. TrimRx also has the lower starting price at $299/follow-up package after a $199 first month (billing period not stated).
How much does TrimRx cost vs MangoRx?
TrimRx is from $299/follow-up package after a $199 first month (billing period not stated) and MangoRx is from $299/mo (shipped monthly; plan length not stated). Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between TrimRx and MangoRx?
TrimRx (5.8/10, #52 of 53) and MangoRx (5.5/10, #53 of 53) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does TrimRx or MangoRx take insurance?
Neither TrimRx nor MangoRx typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Pick the program” links may be affiliate links that support our work. Educational information only. Not medical advice.