MEDGm vs Sesame: Which GLP-1 Clinic Is Better in 2026?
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Short answer
MEDGm wins overall, scoring 7.6/10 vs 7.5/10. Mainly on medication options.
MEDGm wins overall, scoring 7.6/10 vs 7.5/10.
MEDGm · from $169/mo on a 12-month plan paid upfront ($2,028)
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MMEDGm
A full public plan grid, a named medical group and included labs, with compounded injections, tablets and brand-name options. The lowest monthly rate requires a prepaid year, and its refund documents disagree.
from $169/mo on a 12-month plan paid upfront ($2,028)
Visit →SSesame
A clinician marketplace for brand-name GLP-1s: you choose the provider, pay a care fee from $59/mo on a 12-month plan billed once, and buy the medication separately, from $149/mo for the Wegovy pill or Foundayo.
from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately
Visit →Is Sesame legit?MEDGm vs Sesame, side by side
| Feature | MEDGm | Sesame |
|---|---|---|
| Our score | 7.6/10 | 7.5/10 |
| Starting price | $169/mo on a 12-month plan paid upfront ($2,028) | $59/mo care fee on a 12-month plan billed once ($708), medication billed separately |
| Medication types | compounded semaglutide injection, compounded tirzepatide injection, compounded semaglutide tablets, Zepbound (brand), Wegovy (brand), Ozempic (brand) | Wegovy, Wegovy Pill, Zepbound, Foundayo |
| Best for | — | — |
| Overall ranking | #12 | #14 |
| Price & Value (25%) | 7.0 | not scored (counted at 7.0) |
| Clinical Oversight (30%) | 8.0 | 8.0 |
| Medication Options (20%) | 8.5 | 8.0 |
| Transparency (25%) | 7.0 | 7.0 |
Sources: MEDGm pricing verified on medgm.org, Sesame pricing verified on sesamecare.com
Pros & cons
MEDGm
Pros
- + Publishes each compounded plan with its monthly rate and upfront total
- + Names OpenLoop Health and lists pharmacy partners in its terms
- + Includes lab work, clinician support and dose adjustments in compounded plans
Cons
Sesame
Pros
- + Says next to the price that medication is paid separately, gives a floor for it, and prints the price of each medication on the same page
- + You choose your provider from named clinicians, with video visits, messaging and labs at Quest included in the care fee (except in nine states)
- + Brand-name Wegovy (pen and pill), Zepbound and Foundayo, picked up the same day at your pharmacy or delivered
- + Publishes its refund and cancellation terms and the billing schedule of every plan
Cons
- − Weaker on Medication Options (8.0/10 vs 8.5)
The bottom line
After scoring all 61 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), MEDGm (7.6/10) comes out ahead of Sesame (7.5/10). But the right choice still depends on what matters most to you.
MEDGm. From $169/mo on a 12-month plan paid upfront ($2,028).
Visit →Sesame. From $59/mo care fee on a 12-month plan billed once ($708), medication billed separately.
Visit →Editor's overall pick
Not sold on either? Our highest-rated partner clinic outside this pair is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is MEDGm.
Frequently asked questions
Which is better, MEDGm or Sesame?
MEDGm scores higher overall (7.6/10 vs 7.5/10) and is our recommended pick for most people.
How much does MEDGm cost vs Sesame?
MEDGm is from $169/mo on a 12-month plan paid upfront ($2,028) and Sesame is from $59/mo care fee on a 12-month plan billed once ($708), medication billed separately. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between MEDGm and Sesame?
MEDGm (7.6/10, #12 of 61) and Sesame (7.5/10, #14 of 61) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does MEDGm or Sesame take insurance?
Insurance terms differ by clinic and by drug: some clinics are cash-pay only, and some help with insurance for brand-name drugs. Each clinic's review says what it publishes. HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.