GMy GLP-1 Guides

yourEra vs Sesame Care: Which GLP-1 Clinic Is Better in 2026?

41 clinics scored independentlyPrices checked weekly✓ Commissions never move our rankings

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Short answer

yourEra wins overall, scoring 7.4/10 vs 7.1/10 — mainly on price & value and transparency. If price is your priority, Sesame Care is cheaper at $59/mo.

Our pick: yourEra

yourEra wins overall, scoring 7.4/10 vs 7.1/10. If price is your priority, Sesame Care is cheaper at $59/mo.

Winner
#17 of 41

yourEra

7.4

The lowest recurring GLP-1 rate in this ranking at $79.20/mo — for a six-month commitment whose exit terms are not published, from a clinic that names neither its pharmacy, nor its medical group, nor the states it serves.

from $79.20/mo

Visit yourEra
#28 of 41

Sesame Care

7.1

A telehealth marketplace with its own weight-loss subscription — Success by Sesame from $59/mo on the annual plan ($99 month-to-month) covers ongoing care, with medication billed separately from around $249/mo and brand-name Wegovy options through partner pharmacies.

from $59/mo

Visit Sesame Care

yourEra vs Sesame Care, side by side

FeatureyourEraSesame Care
Our score7.4/107.1/10
Starting price$79.20/mo$59/mo
Medication typescompounded semaglutide, compounded tirzepatidecompounded semaglutide, brand-name semaglutide (Wegovy)
Best for
Overall ranking#17#28
Price & Value (25%)8.57.0
Clinical Oversight (30%)7.07.0
Medication Options (20%)7.57.5
Transparency (25%)6.57.0

Sources: yourEra pricing verified on yourera.com, Sesame Care pricing verified on sesamecare.com

Pros & cons

yourEra

Pros

  • + $79.20/mo for compounded semaglutide is the cheapest recurring rate of any clinic we track, and the 20% discount is applied automatically rather than hidden behind a code
  • + Publishes a short, unambiguous refund policy and a real street address, and states the compounded-is-not-FDA-approved disclaimer prominently rather than in the footer alone
  • + Terms of Service are current (March 2026) and spell out the auto-renewal mechanics, the 2-day cancellation window and the arbitration opt-out

Cons

  • Weaker on Transparency (6.5/10)
  • Weaker on Clinical Oversight (7.0/10)
  • Weaker on Medication Options (7.5/10)

Sesame Care

Pros

  • + Four published commitment tiers — $59/mo annual down from $99/mo month-to-month
  • + Offers both compounded and brand-name Wegovy paths
  • + Backed by a large, well-funded telehealth marketplace with broad physician network

Cons

  • Weaker on Price & Value (7.0/10)
  • Weaker on Clinical Oversight (7.0/10)
  • Weaker on Transparency (7.0/10)

The bottom line

After scoring all 41 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), yourEra (7.4/10) comes out ahead of Sesame Care (7.1/10) — but the right choice still depends on what matters most to you.

Choose yourEra if you want this optionfrom $79.20/mo.

Visit yourEra

Choose Sesame Care if you want this optionfrom $59/mo.

Visit Sesame Care

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Wellorithm (8.3/10) from $147/mo — read the review →

Ready to start GLP-1 weight loss?

Our verdict for this matchup is yourEra.

Frequently asked questions

Which is better, yourEra or Sesame Care?

yourEra scores higher overall (7.4/10 vs 7.1/10) and is our recommended pick for most people. If price is the priority, Sesame Care starts at $59/mo.

How much does yourEra cost vs Sesame Care?

yourEra is from $79.20/mo and Sesame Care is from $59/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.

What is the difference between yourEra and Sesame Care?

yourEra (7.4/10, #17 of 41) and Sesame Care (7.1/10, #28 of 41) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.

Does yourEra or Sesame Care take insurance?

Neither yourEra nor Sesame Care typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

Wellorithm vs yourEraWellorithm vs Sesame CareRo (Body by Ro) vs yourEraRo (Body by Ro) vs Sesame CarebmiMD vs yourErabmiMD vs Sesame Care

Top picks

Wellorithm

8.3

from $147/mo

Ro (Body by Ro)

8.3

from $145/mo

bmiMD

7.9

from $99/mo

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.

Top Pick · $147/mo

Wellorithm

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$147/mo is verified as the full, all-inclusive price — consultation and delivery included, with nothing material left out.