Sesame Care vs LifeMD: Which GLP-1 Clinic Is Better in 2026?
Sesame Care wins overall, scoring 7.2/10 vs 7.0/10.
Sesame Care
A pay-per-visit telehealth marketplace rather than a subscription clinic — a $99/28-day membership covers ongoing care, with compounded semaglutide available from around $249/mo and brand-name Wegovy options through partner pharmacies.
from $99/mo
Visit Sesame CareLifeMD
A publicly traded (NASDAQ: LFMD) multi-specialty telehealth platform's GLP-1 arm — compounded semaglutide from $149/mo on a 6-month plan, plus a separate membership fee and a branded-Wegovy pathway via a Novo Nordisk partnership.
from $149/mo
Visit LifeMDSesame Care vs LifeMD, side by side
| Feature | Sesame Care | LifeMD |
|---|---|---|
| Our score | 7.2/10 | 7.0/10 |
| Starting price | $99/mo | $149/mo |
| Medication types | compounded semaglutide, brand-name semaglutide (Wegovy) | compounded semaglutide, compounded tirzepatide, brand-name Wegovy |
| Best for | — | — |
| Overall ranking | #20 | #25 |
| Price & Value (25%) | 7.0 | 6.5 |
| Clinical Oversight (25%) | 7.0 | 7.5 |
| Medication Options (20%) | 7.5 | 7.5 |
| User Experience (15%) | 7.5 | 7.5 |
| Transparency (15%) | 7.0 | 6.0 |
Pros & cons
Sesame Care
Pros
- + Marketplace model: pay for care access ($99/28 days) without a long-term program lock-in
- + Offers both compounded and brand-name Wegovy paths
- + Backed by a large, well-funded telehealth marketplace with broad physician network
Cons
- − Weaker on Price & Value (7.0/10)
- − Weaker on Clinical Oversight (7.0/10)
- − Weaker on Transparency (7.0/10)
LifeMD
Pros
- + Established, publicly traded telehealth infrastructure predating the GLP-1 wave
- + Both compounded and branded-Wegovy medication pathways
- + 6-month compounded semaglutide plan from $149/mo
Cons
- − Weaker on Transparency (6.0/10)
- − Weaker on Price & Value (6.5/10)
- − Weaker on Clinical Oversight (7.5/10)
The bottom line
After scoring all 28 clinics on price, clinical oversight, medication options, experience and transparency, Sesame Care (7.2/10) comes out ahead of LifeMD (7.0/10) — but the right choice depends on what matters most to you.
Choose Sesame Care if you want this option — from $99/mo.
Visit Sesame Care →Choose LifeMD if you want this option — from $149/mo.
Visit LifeMD →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Gala Health (8.3/10) from $149/mo — read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is Sesame Care.
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How we score: every clinic is rated on five weighted criteria from documented evidence, re-verified monthly. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.