Sesame Care vs Calibrate: Which GLP-1 Clinic Is Better in 2026?
Sesame Care wins overall, scoring 7.2/10 vs 7.1/10.
Sesame Care
A pay-per-visit telehealth marketplace rather than a subscription clinic — a $99/28-day membership covers ongoing care, with compounded semaglutide available from around $249/mo and brand-name Wegovy options through partner pharmacies.
from $99/mo
Visit Sesame CareCalibrate
A metabolic-health program built around GLP-1 medication plus a structured coaching curriculum — the $199/mo program fee (3-month minimum) covers coaching and clinician oversight, while medication itself is billed through insurance separately.
from $199/mo
Visit CalibrateSesame Care vs Calibrate, side by side
| Feature | Sesame Care | Calibrate |
|---|---|---|
| Our score | 7.2/10 | 7.1/10 |
| Starting price | $99/mo | $199/mo |
| Medication types | compounded semaglutide, brand-name semaglutide (Wegovy) | GLP-1 medication (insurance-billed), metabolic coaching curriculum |
| Best for | — | Most Structured Coaching Program |
| Overall ranking | #18 | #20 |
| Price & Value (25%) | 7.0 | 6.0 |
| Clinical Oversight (25%) | 7.0 | 8.0 |
| Medication Options (20%) | 7.5 | 7.0 |
| User Experience (15%) | 7.5 | 8.0 |
| Transparency (15%) | 7.0 | 6.5 |
Pros & cons
Sesame Care
Pros
- + Marketplace model: pay for care access ($99/28 days) without a long-term program lock-in
- + Offers both compounded and brand-name Wegovy paths
- + Backed by a large, well-funded telehealth marketplace with broad physician network
Cons
- − Weaker on Price & Value (7.0/10)
- − Weaker on Clinical Oversight (7.0/10)
- − Weaker on Transparency (7.0/10)
Calibrate
Pros
- + Structured metabolic-health curriculum alongside medication management
- + Clinician-supervised program with an established multi-year track record
- + Works with insurance for the medication itself rather than cash-pay compounding
Cons
- − Weaker on Price & Value (6.0/10)
- − Weaker on Transparency (6.5/10)
- − Weaker on Medication Options (7.0/10)
The bottom line
After scoring all 22 clinics on price, clinical oversight, medication options, experience and transparency, Sesame Care (7.2/10) comes out ahead of Calibrate (7.1/10) — but the right choice depends on what matters most to you.
Choose Sesame Care if you want this option — from $99/mo.
Visit Sesame Care →Choose Calibrate if you want most structured coaching program — from $199/mo.
Visit Calibrate →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Gala Health (8.3/10) from $149/mo — read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is Sesame Care.
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How we score: every clinic is rated on five weighted criteria from documented evidence, re-verified monthly. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.