HealthRX vs Enhance.MD: Which GLP-1 Clinic Is Better in 2026?
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Short answer
HealthRX wins overall, scoring 7.8/10 vs 7.5/10. Mainly on price & value and medication options.
HealthRX wins overall, scoring 7.8/10 vs 7.5/10.
HealthRX · from $99/mo on a $1,188 prepaid year
A low-priced, heavily-credentialed option. Compounded semaglutide from $99/mo, reviewed within 24h by independent US board-certified physicians, dispensed by a LegitScript-certified 503A pharmacy with free overnight shipping and a 30-day money-back guarantee.
from $99/mo on a $1,188 prepaid year
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One of the few clinics here that names its actual pharmacies and medical groups, publishes every plan length with its billing cadence, and bundles metabolic lab work every six months. But it's priced at the top of this set and it doesn't ship to 11 states.
from $212/mo, billed every 48 weeks
Visit Enhance.MDHealthRX vs Enhance.MD, side by side
| Feature | HealthRX | Enhance.MD |
|---|---|---|
| Our score | 7.8/10 | 7.5/10 |
| Starting price | $99/mo on a $1,188 prepaid year | $212/mo, billed every 48 weeks |
| Medication types | compounded semaglutide, compounded tirzepatide | compounded semaglutide, compounded tirzepatide, compounded semaglutide + tirzepatide, microdosing |
| Best for | — | — |
| Overall ranking | #3 | #14 |
| Price & Value (25%) | 7.5 | 6.0 |
| Clinical Oversight (30%) | 8.0 | 8.0 |
| Medication Options (20%) | 7.5 | 8.0 |
| Transparency (25%) | 8.0 | 8.0 |
Sources: HealthRX pricing verified on healthrx.com, Enhance.MD pricing verified on enhance.md
Pros & cons
HealthRX
Pros
- + Compounded semaglutide from $99/mo on the 12-month plan
- + US board-certified physician review within 24h; LegitScript-certified 503A pharmacy
- + Free overnight shipping plus a 30-day money-back guarantee
Cons
- − Weaker on Price & Value (7.5/10)
- − Weaker on Medication Options (7.5/10)
- − Weaker on Clinical Oversight (8.0/10)
Enhance.MD
Pros
- + Publishes the full price grid (all four plan lengths, each with its billing cadence) plus the same price at every dose
- + Names all three partner pharmacies and both medical groups on its own site, which almost nobody in this category does
- + Metabolic lab testing every 6 months and ongoing provider care included in the monthly price, no separate membership fee
Cons
- − Not available in 11 states
- − Weaker on Price & Value (6.0/10)
- − Weaker on Clinical Oversight (8.0/10)
The bottom line
After scoring all 53 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), HealthRX (7.8/10) comes out ahead of Enhance.MD (7.5/10). But the right choice still depends on what matters most to you.
Choose HealthRX if you want this option. From $99/mo on a $1,188 prepaid year.
Pick the program →Choose Enhance.MD if you want this option. From $212/mo, billed every 48 weeks.
Visit Enhance.MD →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is HealthRX.
Frequently asked questions
Which is better, HealthRX or Enhance.MD?
HealthRX scores higher overall (7.8/10 vs 7.5/10) and is our recommended pick for most people. HealthRX also has the lower starting price at $99/mo on a $1,188 prepaid year.
How much does HealthRX cost vs Enhance.MD?
HealthRX is from $99/mo on a $1,188 prepaid year and Enhance.MD is from $212/mo, billed every 48 weeks. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between HealthRX and Enhance.MD?
HealthRX (7.8/10, #3 of 53) and Enhance.MD (7.5/10, #14 of 53) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does HealthRX or Enhance.MD take insurance?
Neither HealthRX nor Enhance.MD typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Pick the program” links may be affiliate links that support our work. Educational information only. Not medical advice.