Yucca Health vs LifeMD: Which GLP-1 Clinic Is Better in 2026?
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Short answer
Yucca Health wins overall, scoring 7.9/10 vs 7.0/10. Mainly on transparency and medication options.
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Yucca Health
A clean, value-first option: compounded semaglutide from $69/mo on a 12-month plan ($828 billed every 12 months), free 2-day shipping, though it does not name the pharmacy that fills prescriptions. Both GLP-1 injectables, nationwide.
from $69/mo on a 12-month plan, $828 billed every 12 months
Read Review →Is Yucca Health legit?
A publicly traded telehealth company (NASDAQ: LFMD) prescribing only brand-name GLP-1s, including the Wegovy pill, Zepbound and Foundayo, at manufacturer cash prices. The $149 headline is the medication alone: a $149 monthly program fee sits on top, disclosed only in a footnote.
from $149/mo for the Wegovy pill (1.5 mg), plus a separate program fee
Read Review →Yucca Health vs LifeMD, side by side
| Feature | Yucca Health | LifeMD |
|---|---|---|
| Our score | 7.9/10 | 7.0/10 |
| Starting price | $69/mo on a 12-month plan, $828 billed every 12 months | $149/mo for the Wegovy pill (1.5 mg), plus a separate program fee |
| Medication types | compounded semaglutide, compounded tirzepatide | brand-name Wegovy pen, brand-name Wegovy pill (oral semaglutide), brand-name Zepbound (vial, pen, KwikPen), brand-name Foundayo (oral orforglipron), brand-name Saxenda, brand-name Ozempic (off-label), Triple Therapy (metformin, bupropion, topiramate) |
| Best for | Best Value | — |
| Overall ranking | #3 | #40 |
| Price & Value (25%) | 8.5 | not scored (counted at 5.5) |
| Clinical Oversight (30%) | 8.0 | 8.0 |
| Medication Options (20%) | 7.5 | 9.0 |
| Transparency (25%) | 7.5 | 5.5 |
Sources: Yucca Health pricing verified on tryyucca.com, LifeMD pricing verified on lifemd.com
Pros & cons
Yucca Health
Pros
- + $69/mo on a 12-month semaglutide plan, the same price at every dose
- + Free UPS 2-Day Air, kit included, 24/7 care team
- + LegitScript-certified, licensed-provider review in ~24h
Cons
- − Weaker on Medication Options (7.5/10 vs 9.0)
LifeMD
Pros
- + Brand-name only, across four molecules and both routes: Wegovy pen and pill, Zepbound vial and pens, Foundayo, Saxenda. No compounded GLP-1 is sold
- + Publicly traded (NASDAQ: LFMD), with a named legal entity and street address, nine named affiliated medical practices, and an A rating from the BBB
- + Metabolic lab work at Quest or Labcorp is included in the program fee outside NY, NJ and RI, and the team runs insurance benefit checks and prior authorizations
Cons
- − Weaker on Transparency (5.5/10 vs 7.5)
The bottom line
After scoring all 61 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), Yucca Health (7.9/10) comes out ahead of LifeMD (7.0/10). But the right choice still depends on what matters most to you.
Yucca Health. From $69/mo on a 12-month plan, $828 billed every 12 months.
Read Review →LifeMD. From $149/mo for the Wegovy pill (1.5 mg), plus a separate program fee.
Read Review →Editor's overall pick
Not sold on either? Our highest-rated partner clinic outside this pair is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →
Ready to start GLP-1 weight loss?
Yucca Health scores higher on our rubric. It is not one of our partners.
Frequently asked questions
Which is better, Yucca Health or LifeMD?
Yucca Health scores higher overall (7.9/10 vs 7.0/10) on our rubric.
How much does Yucca Health cost vs LifeMD?
Yucca Health is from $69/mo on a 12-month plan, $828 billed every 12 months and LifeMD is from $149/mo for the Wegovy pill (1.5 mg), plus a separate program fee. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Yucca Health and LifeMD?
Yucca Health (7.9/10, #3 of 61) and LifeMD (7.0/10, #40 of 61) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Yucca Health or LifeMD take insurance?
Insurance terms differ by clinic and by drug: some clinics are cash-pay only, and some help with insurance for brand-name drugs. Each clinic's review says what it publishes. HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.