HealthRX vs RxSpan MD: Which GLP-1 Clinic Is Better in 2026?
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Short answer
HealthRX wins overall, scoring 7.8/10 vs 7.3/10. Mainly on price & value and medication options.
HealthRX wins overall, scoring 7.8/10 vs 7.3/10.
HealthRX · from $99/mo on a $1,188 prepaid year
A low-priced, heavily-credentialed option. Compounded semaglutide from $99/mo, reviewed within 24h by independent US board-certified physicians, dispensed by a LegitScript-certified 503A pharmacy with free overnight shipping and a 30-day money-back guarantee.
from $99/mo on a $1,188 prepaid year
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Both GLP-1 molecules in both routes plus three real brand names, and the most rigorously sourced medication-comparison page of any clinic we track. From a practice that publishes neither its pharmacy, nor the states it ships to, nor any refund terms behind a $2,094 upfront charge.
from $175/mo on a $2,094 upfront 12-month plan
Visit →HealthRX vs RxSpan MD, side by side
| Feature | HealthRX | RxSpan MD |
|---|---|---|
| Our score | 7.8/10 | 7.3/10 |
| Starting price | $99/mo on a $1,188 prepaid year | $175/mo on a $2,094 upfront 12-month plan |
| Medication types | compounded semaglutide, compounded tirzepatide | compounded semaglutide, compounded tirzepatide, oral semaglutide capsules, oral tirzepatide capsules, brand-name Ozempic/Wegovy/Zepbound |
| Best for | — | — |
| Overall ranking | #3 | #19 |
| Price & Value (25%) | 7.5 | 6.0 |
| Clinical Oversight (30%) | 8.0 | 8.0 |
| Medication Options (20%) | 7.5 | 9.0 |
| Transparency (25%) | 8.0 | 6.5 |
Sources: HealthRX pricing verified on healthrx.com, RxSpan MD pricing verified on rxspanmd.com
Pros & cons
HealthRX
Pros
- + Compounded semaglutide from $99/mo on the 12-month plan
- + US board-certified physician review within 24h; LegitScript-certified 503A pharmacy
- + Free overnight shipping plus a 30-day money-back guarantee
Cons
- − Weaker on Price & Value (7.5/10)
- − Weaker on Medication Options (7.5/10)
- − Weaker on Clinical Oversight (8.0/10)
RxSpan MD
Pros
- + Semaglutide and tirzepatide in injection AND oral-capsule form, plus cash-pay Ozempic, Wegovy and Zepbound
- + Founding physician named and independently verifiable. Dr. John Diaz, MD, FACS, board-certified by the American Board of Plastic Surgery
- + Publishes the pre-discount rate next to the promo rate, and the full plan grid with the actual upfront dollar amount for each term
Cons
- − Weaker on Price & Value (6.0/10)
- − Weaker on Transparency (6.5/10)
- − Weaker on Clinical Oversight (8.0/10)
The bottom line
After scoring all 53 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), HealthRX (7.8/10) comes out ahead of RxSpan MD (7.3/10). But the right choice still depends on what matters most to you.
Choose HealthRX if you want this option. From $99/mo on a $1,188 prepaid year.
Visit →Choose RxSpan MD if you want this option. From $175/mo on a $2,094 upfront 12-month plan.
Visit →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is HealthRX.
Frequently asked questions
Which is better, HealthRX or RxSpan MD?
HealthRX scores higher overall (7.8/10 vs 7.3/10) and is our recommended pick for most people. HealthRX also has the lower starting price at $99/mo on a $1,188 prepaid year.
How much does HealthRX cost vs RxSpan MD?
HealthRX is from $99/mo on a $1,188 prepaid year and RxSpan MD is from $175/mo on a $2,094 upfront 12-month plan. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between HealthRX and RxSpan MD?
HealthRX (7.8/10, #3 of 53) and RxSpan MD (7.3/10, #19 of 53) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does HealthRX or RxSpan MD take insurance?
Neither HealthRX nor RxSpan MD typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit” links may be affiliate links that support our work. Educational information only. Not medical advice.