GMy GLP-1 Guides

HealthRX vs Calibrate: Which GLP-1 Clinic Is Better in 2026?

✓ 53 clinics scored independently✓ Prices checked weekly✓ Scores from evidence · partners first at equal scores

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Short answer

HealthRX wins overall, scoring 7.8/10 vs 7.0/10. Mainly on transparency and medication options.

Our pick: HealthRX

HealthRX wins overall, scoring 7.8/10 vs 7.0/10.

HealthRX · from $99/mo on a $1,188 prepaid year

Winner
#3 of 53

HealthRX

7.8

A low-priced, heavily-credentialed option. Compounded semaglutide from $99/mo, reviewed within 24h by independent US board-certified physicians, dispensed by a LegitScript-certified 503A pharmacy with free overnight shipping and a 30-day money-back guarantee.

from $99/mo on a $1,188 prepaid year

Pick the program →
#32 of 53

CalibrateCalibrate

7.0

A coaching-first GLP-1 program that prescribes only brand-name medication through your commercial insurance. The $199/mo is a membership on a locked 3-month minimum, with medication and labs billed separately, and it does not accept uninsured patients or Medicare, Medicaid, Tricare or Kaiser members.

from $199/mo membership, 3-month minimum ($597), medication and labs billed through your insurance

Visit Calibrate

HealthRX vs Calibrate, side by side

FeatureHealthRXCalibrate
Our score7.8/107.0/10
Starting price$99/mo on a $1,188 prepaid year$199/mo membership, 3-month minimum ($597), medication and labs billed through your insurance
Medication typescompounded semaglutide, compounded tirzepatidebrand-name Zepbound, brand-name Wegovy (injection or pill), brand-name Foundayo (oral orforglipron), brand-name Mounjaro, brand-name Ozempic, brand-name Saxenda, brand-name Trulicity, brand-name Rybelsus
Best for——
Overall ranking#3#32
Price & Value (25%)7.5not scored (counted at 6.0)
Clinical Oversight (30%)8.08.0
Medication Options (20%)7.58.0
Transparency (25%)8.06.0

Sources: HealthRX pricing verified on healthrx.com, Calibrate pricing verified on joincalibrate.com

Pros & cons

HealthRX

Pros

  • + Compounded semaglutide from $99/mo on the 12-month plan
  • + US board-certified physician review within 24h; LegitScript-certified 503A pharmacy
  • + Free overnight shipping plus a 30-day money-back guarantee

Cons

  • − Weaker on Price & Value (7.5/10)
  • − Weaker on Medication Options (7.5/10)
  • − Weaker on Clinical Oversight (8.0/10)

Calibrate

Pros

  • + Brand-name only, and says so plainly: its own FAQ states it does not prescribe compounded GLP-1s because they are not FDA-approved
  • + Live 1:1 video visit with a clinician who reviews six named lab tests before prescribing, plus coaching every two weeks and medical check-ins through the app
  • + Publishes its full membership terms, cancellation policy and money-back terms (50% back if you lose under 10% after 12 consecutive months, with conditions)

Cons

  • − Weaker on Transparency (6.0/10)
  • − Weaker on Clinical Oversight (8.0/10)
  • − Weaker on Medication Options (8.0/10)

The bottom line

After scoring all 53 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), HealthRX (7.8/10) comes out ahead of Calibrate (7.0/10). But the right choice still depends on what matters most to you.

Choose HealthRX if you want this option. From $99/mo on a $1,188 prepaid year.

Pick the program →

Choose Calibrate if you want this option. From $199/mo membership, 3-month minimum ($597), medication and labs billed through your insurance.

Visit Calibrate →

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Wellorithm (7.9/10) from $247/mo after month 1. Read the review →

Ready to start GLP-1 weight loss?

Our verdict for this matchup is HealthRX.

HealthRX · from $99/mo on a $1,188 prepaid yearPick the program →
See full rankings

Frequently asked questions

Which is better, HealthRX or Calibrate?

HealthRX scores higher overall (7.8/10 vs 7.0/10) and is our recommended pick for most people. HealthRX also has the lower starting price at $99/mo on a $1,188 prepaid year.

How much does HealthRX cost vs Calibrate?

HealthRX is from $99/mo on a $1,188 prepaid year and Calibrate is from $199/mo membership, 3-month minimum ($597), medication and labs billed through your insurance. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.

What is the difference between HealthRX and Calibrate?

HealthRX (7.8/10, #3 of 53) and Calibrate (7.0/10, #32 of 53) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.

Does HealthRX or Calibrate take insurance?

Neither HealthRX nor Calibrate typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

Wellorithm vs HealthRX→Wellorithm vs Calibrate→Lavender Sky Health vs HealthRX→Lavender Sky Health vs Calibrate→Pallas Health vs HealthRX→HealthRX vs Ro (Body by Ro)→

Top picks

Wellorithm

7.9

from $247/mo from month 2 ($147 first month)

Lavender Sky Health

7.9

from $78/mo equivalent on an 8 to 10 week supply

HealthRX

7.8

from $99/mo on a $1,188 prepaid year

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How we score: every clinic is rated on 4 weighted criteria from documented evidence. Prices checked weekly. See each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Pick the program” links may be affiliate links that support our work. Educational information only. Not medical advice.