Enhance.MD vs He & She MD: Which GLP-1 Clinic Is Better in 2026?
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Short answer
Enhance.MD wins overall, scoring 7.5/10 vs 7.3/10 — mainly on transparency and price & value. If price is your priority, He & She MD is cheaper at $99/mo.
Enhance.MD wins overall, scoring 7.5/10 vs 7.3/10. If price is your priority, He & She MD is cheaper at $99/mo.
Enhance.MD
One of the few clinics here that names its actual pharmacies and medical groups, publishes every plan length with its billing cadence, and bundles metabolic lab work every six months — but it's priced at the top of this set and it doesn't ship to 11 states.
from $212/mo
Visit Enhance.MDHe & She MD
Two GLP-1 molecules in both injection and oral form plus cash-pay Ozempic and Zepbound, at the joint-lowest entry rate we track — from a site that publishes two contradictory price grids for the same medication and advertises a 4.9 rating on a Trustpilot profile holding zero reviews.
from $99/mo
Visit He & She MDEnhance.MD vs He & She MD, side by side
| Feature | Enhance.MD | He & She MD |
|---|---|---|
| Our score | 7.5/10 | 7.3/10 |
| Starting price | $212/mo | $99/mo |
| Medication types | compounded semaglutide, compounded tirzepatide, compounded semaglutide + tirzepatide, microdosing, NAD+ | compounded semaglutide, compounded tirzepatide, oral semaglutide, oral tirzepatide, brand-name Ozempic/Zepbound |
| Best for | — | — |
| Overall ranking | #16 | #22 |
| Price & Value (25%) | 6.0 | 7.5 |
| Clinical Oversight (30%) | 8.0 | 7.5 |
| Medication Options (20%) | 8.0 | 9.0 |
| Transparency (25%) | 8.0 | 5.5 |
Sources: Enhance.MD pricing verified on enhance.md, He & She MD pricing verified on heandshemd.com
Pros & cons
Enhance.MD
Pros
- + Publishes the full price grid — all four plan lengths, each with its billing cadence — plus the same price at every dose
- + Names all three partner pharmacies and both medical groups on its own site, which almost nobody in this category does
- + Metabolic lab testing every 6 months and ongoing provider care included in the monthly price, no separate membership fee
Cons
- − Not available in 11 states
- − Weaker on Price & Value (6.0/10)
- − Weaker on Clinical Oversight (8.0/10)
He & She MD
Pros
- + $99/mo on the annual plan ties HealthRX for the lowest recurring GLP-1 rate in this ranking, with the $1,188 upfront total printed on the page
- + Publishes a real states-served exclusion list — no shipping to New Jersey, Mississippi, Alaska or Hawaii — which most clinics here do not publish at all
- + Names the medical group that treats you (Beluga Health, P.A.) in its Terms of Service, and offers both molecules in both injection and oral form plus brand-name Ozempic and Zepbound
Cons
- − Not available in 4 states
- − Weaker on Transparency (5.5/10)
- − Weaker on Price & Value (7.5/10)
The bottom line
After scoring all 41 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), Enhance.MD (7.5/10) comes out ahead of He & She MD (7.3/10) — but the right choice still depends on what matters most to you.
Choose Enhance.MD if you want this option — from $212/mo.
Visit Enhance.MD →Choose He & She MD if you want this option — from $99/mo.
Visit He & She MD →Editor's overall pick
Not sold on either? Our highest-rated clinic overall is Wellorithm (8.3/10) from $147/mo — read the review →
Ready to start GLP-1 weight loss?
Our verdict for this matchup is Enhance.MD.
Frequently asked questions
Which is better, Enhance.MD or He & She MD?
Enhance.MD scores higher overall (7.5/10 vs 7.3/10) and is our recommended pick for most people. If price is the priority, He & She MD starts at $99/mo.
How much does Enhance.MD cost vs He & She MD?
Enhance.MD is from $212/mo and He & She MD is from $99/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.
What is the difference between Enhance.MD and He & She MD?
Enhance.MD (7.5/10, #16 of 41) and He & She MD (7.3/10, #22 of 41) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.
Does Enhance.MD or He & She MD take insurance?
Neither Enhance.MD nor He & She MD typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.
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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.