GMy GLP-1 Guides

yourEra vs RxSpan MD: Which GLP-1 Clinic Is Better in 2026?

41 clinics scored independentlyPrices checked weekly✓ Commissions never move our rankings

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Short answer

yourEra wins overall, scoring 7.4/10 vs 7.3/10 — mainly on price & value and medication options.

Our pick: yourEra

yourEra wins overall, scoring 7.4/10 vs 7.3/10.

Winner
#17 of 41

yourEra

7.4

The lowest recurring GLP-1 rate in this ranking at $79.20/mo — for a six-month commitment whose exit terms are not published, from a clinic that names neither its pharmacy, nor its medical group, nor the states it serves.

from $79.20/mo

Visit yourEra
#21 of 41

RxSpan MD

7.3

Both GLP-1 molecules in both routes plus three real brand names, and the most rigorously sourced medication-comparison page of any clinic we track — from a practice that publishes neither its pharmacy, nor the states it ships to, nor any refund terms behind a $2,327 upfront charge.

from $175/mo

Visit RxSpan MD

yourEra vs RxSpan MD, side by side

FeatureyourEraRxSpan MD
Our score7.4/107.3/10
Starting price$79.20/mo$175/mo
Medication typescompounded semaglutide, compounded tirzepatidecompounded semaglutide, compounded tirzepatide, oral semaglutide capsules, oral tirzepatide capsules, brand-name Ozempic/Wegovy/Zepbound
Best for
Overall ranking#17#21
Price & Value (25%)8.56.0
Clinical Oversight (30%)7.08.0
Medication Options (20%)7.59.0
Transparency (25%)6.56.5

Sources: yourEra pricing verified on yourera.com, RxSpan MD pricing verified on rxspanmd.com

Pros & cons

yourEra

Pros

  • + $79.20/mo for compounded semaglutide is the cheapest recurring rate of any clinic we track, and the 20% discount is applied automatically rather than hidden behind a code
  • + Publishes a short, unambiguous refund policy and a real street address, and states the compounded-is-not-FDA-approved disclaimer prominently rather than in the footer alone
  • + Terms of Service are current (March 2026) and spell out the auto-renewal mechanics, the 2-day cancellation window and the arbitration opt-out

Cons

  • Weaker on Transparency (6.5/10)
  • Weaker on Clinical Oversight (7.0/10)
  • Weaker on Medication Options (7.5/10)

RxSpan MD

Pros

  • + Semaglutide and tirzepatide in injection AND oral-capsule form, plus cash-pay Ozempic, Wegovy and Zepbound
  • + Founding physician named and independently verifiable — Dr. John Diaz, MD, FACS, board-certified by the American Board of Plastic Surgery
  • + Publishes the pre-discount rate next to the promo rate, and the full plan grid with the actual upfront dollar amount for each term

Cons

  • Weaker on Price & Value (6.0/10)
  • Weaker on Transparency (6.5/10)
  • Weaker on Clinical Oversight (8.0/10)

The bottom line

After scoring all 41 clinics on our 4-criterion rubric (price & value, clinical oversight, medication options and transparency), yourEra (7.4/10) comes out ahead of RxSpan MD (7.3/10) — but the right choice still depends on what matters most to you.

Choose yourEra if you want this optionfrom $79.20/mo.

Visit yourEra

Choose RxSpan MD if you want this optionfrom $175/mo.

Visit RxSpan MD

Editor's overall pick

Not sold on either? Our highest-rated clinic overall is Wellorithm (8.3/10) from $147/mo — read the review →

Ready to start GLP-1 weight loss?

Our verdict for this matchup is yourEra.

Frequently asked questions

Which is better, yourEra or RxSpan MD?

yourEra scores higher overall (7.4/10 vs 7.3/10) and is our recommended pick for most people. yourEra also has the lower starting price at $79.20/mo.

How much does yourEra cost vs RxSpan MD?

yourEra is from $79.20/mo and RxSpan MD is from $175/mo. Both are typically cash-pay; HSA/FSA funds are often eligible. We run an automated check against each clinic's own live pricing page every week; a price left unconfirmed for 45 days shows as unverified rather than staying marked as current.

What is the difference between yourEra and RxSpan MD?

yourEra (7.4/10, #17 of 41) and RxSpan MD (7.3/10, #21 of 41) are scored independently across our 4 criteria: price & value, clinical oversight, medication options and transparency. See the detailed score breakdown above for the criterion-by-criterion comparison.

Does yourEra or RxSpan MD take insurance?

Neither yourEra nor RxSpan MD typically accepts insurance for GLP-1 weight-loss treatment. Both operate on a cash-pay model, though HSA and FSA funds are often eligible. Confirm at checkout.

Related comparisons

Wellorithm vs yourEraWellorithm vs RxSpan MDRo (Body by Ro) vs yourEraRo (Body by Ro) vs RxSpan MDbmiMD vs yourErabmiMD vs RxSpan MD

Top picks

Wellorithm

8.3

from $147/mo

Ro (Body by Ro)

8.3

from $145/mo

bmiMD

7.9

from $99/mo

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How we score: every clinic is rated on five weighted criteria from documented evidence. Prices checked weekly— see each review for that clinic's own verification status. Scores are never influenced by affiliate commissions. “Visit”/“Try” links may be affiliate links that support our work. Educational information only — not medical advice.

Top Pick · $147/mo

Wellorithm

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$147/mo is verified as the full, all-inclusive price — consultation and delivery included, with nothing material left out.